Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528950 | 0.91 | NPC1 (0.39) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8526643 | 0.78 | GABRA5 (0.41) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8527297 | 0.76 | ALDH1A1 (0.39) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8683544 | 0.71 | MAPT (0.44) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10542977 | 0.71 | MAPT (0.44) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8626419 | 0.71 | MAPT (0.44) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11063821 | 0.71 | MAPT (0.38) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL38663127 | 0.71 | MAPT (0.41) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2786880 | 0.71 | TP53 (0.59) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11091142 | 0.70 | PDE5A (0.46) | LMNAMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620228-B1 | Novel reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same | LUCKY LTD (KR) | 1998-03-11 | — | — | EP | claimed |