Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526129 | 0.88 | GABRA5 (0.43) | GABRA5GABRB2HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL8768623 | 0.88 | GABRA5 (0.43) | GABRA5GABRB2HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL8526155 | 0.78 | LMNA (0.36) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL8526934 | 0.70 | GABRA5 (0.49) | GABRA5GABRB2HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL9600369 | 0.68 | SMN1; SMN2 (0.45) | GABRA5GABRB2HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL27683802 | 0.68 | SMN1; SMN2 (0.54) | GABRA5GABRB2HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL3539057 | 0.68 | SMN1; SMN2 (0.52) | GABRA5GABRB2HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL4970134 | 0.65 | SMN1; SMN2 (0.59) | GABRA5GABRB2HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL2456530 | 0.64 | MAPT (0.52) | GABRA5GABRB2HSD17B10RAB9ANPC1 | |
| SCHEMBL9691586 | 0.64 | MAPT (0.52) | GABRA5GABRB2HSD17B10RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620228-B1 | Novel reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same | LUCKY LTD (KR) | 1998-03-11 | — | — | EP | claimed |