Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526155 | 0.91 | LMNA (0.36) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9813156 | 0.79 | LMNA (0.42) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9813145 | 0.79 | LMNA (0.42) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL8526129 | 0.77 | GABRA5 (0.43) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL8768623 | 0.77 | GABRA5 (0.43) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL3997592 | 0.75 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL4001147 | 0.75 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL27815401 | 0.74 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL11092959 | 0.73 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL2786880 | 0.72 | TP53 (0.59) | NPC1RAB9ASMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620228-B1 | Novel reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same | LUCKY LTD (KR) | 1998-03-11 | — | — | EP | claimed |