Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 8/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 8/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 8/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530387 | 0.73 | PRSS1 (0.60) | PRSS1PRSS2PRSS3TPSAB1CTSL | |
| SCHEMBL8526423 | 0.73 | SLC1A3 (0.39) | TGM2HDAC1HDAC2PRSS1PRSS2 | |
| SCHEMBL10704514 | 0.72 | PRSS1 (0.50) | HDAC1HDAC2PRSS1PRSS2PRSS3 | |
| SCHEMBL29087638 | 0.72 | PRSS1 (0.54) | HDAC1HDAC2PRSS1PRSS2PRSS3 | |
| SCHEMBL23044896 | 0.70 | ITGB3 (0.58) | PRSS1PRSS2PRSS3TPSAB1CTSL | |
| SCHEMBL15519969 | 0.70 | ITGB3 (0.58) | PRSS1PRSS2PRSS3TPSAB1CTSL | |
| SCHEMBL1841203 | 0.70 | PRSS1 (0.61) | HDAC1HDAC2PRSS1PRSS2PRSS3 | |
| SCHEMBL10723335 | 0.70 | PRSS1 (0.61) | HDAC1HDAC2PRSS1PRSS2PRSS3 | |
| SCHEMBL1841202 | 0.70 | PRSS1 (0.61) | HDAC1HDAC2PRSS1PRSS2PRSS3 | |
| SCHEMBL7594443 | 0.69 | PRSS1 (0.49) | HDAC1HDAC2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |