Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.57 |
| ▸ | CTSK | P43235 | 5/20 | 0.57 |
| ▸ | CTSB | P07858 | 2/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | REN | P00797 | 5/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8527574 | 0.93 | REN (0.65) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL20204700 | 0.88 | CTSS (0.65) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL28269148 | 0.88 | CTSS (0.65) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL22962275 | 0.88 | CTSS (0.65) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL20204705 | 0.88 | CTSS (0.65) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL8584067 | 0.88 | REN (0.58) | REN | |
| SCHEMBL7373235 | 0.84 | CTSS (0.53) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL30091422 | 0.82 | REN (0.62) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL29787480 | 0.82 | CTSS (0.61) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL22962389 | 0.81 | REN (0.75) | CTSSCTSKCTSBCTSLREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821331-A | INHIBIT THE PROTEOLYTIC ACTIVITY OF PROTEASES | ELI LILLY AND COMPANY (US) | 1998-10-13 | — | — | US | disclosed |