Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 9/20 | 0.65 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | CCKBR | P32239 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584067 | 0.94 | REN (0.58) | REN | |
| SCHEMBL8526669 | 0.93 | CTSS (0.57) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL30091422 | 0.90 | REN (0.62) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL19559785 | 0.87 | REN (0.67) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL8529180 | 0.87 | KISS1R (0.53) | RENCTSB | |
| SCHEMBL20204696 | 0.86 | REN (0.62) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL20204708 | 0.86 | REN (0.62) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL8527576 | 0.85 | BACE1 (0.49) | RENCTSB | |
| SCHEMBL8527552 | 0.84 | PSMB5 (0.49) | CTSBCTSK | |
| SCHEMBL30140924 | 0.83 | REN (0.81) | RENCTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821331-A | INHIBIT THE PROTEOLYTIC ACTIVITY OF PROTEASES | ELI LILLY AND COMPANY (US) | 1998-10-13 | — | — | US | disclosed |