Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.65 |
| ▸ | CTSK | P43235 | 9/20 | 0.65 |
| ▸ | CTSB | P07858 | 5/20 | 0.65 |
| ▸ | CTSL | P07711 | 1/20 | 0.65 |
| ▸ | AKT1 | P31749 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.57 |
| ▸ | REN | P00797 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204700 | 1.00 | CTSS (0.65) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL20204705 | 1.00 | CTSS (0.65) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL28269148 | 1.00 | CTSS (0.65) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL20204696 | 0.91 | REN (0.62) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL20204708 | 0.91 | REN (0.62) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL7094 | 0.90 | ATM (0.62) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL390555 | 0.90 | ATM (0.62) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL1094506 | 0.90 | ATM (0.62) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL8526669 | 0.88 | CTSS (0.57) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL23223551 | 0.87 | CTSK (0.51) | CTSSCTSKCTSBCTSLAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026492-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE AGONISTS | Humanwell Pharmaceutical US (US) | 2021-02-11 | — | — | WO | disclosed |