Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246909 | 0.82 | TSHR (0.36) | ALDH1A1TSHRHSD17B10MAPK1MEN1 | |
| SCHEMBL11140826 | 0.75 | ALDH1A1 (0.30) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL7775161 | 0.73 | TSHR (0.33) | ALDH1A1TSHRHSD17B10THRB | |
| SCHEMBL14469640 | 0.73 | TSHR (0.33) | ALDH1A1TSHRHSD17B10THRB | |
| SCHEMBL24489057 | 0.73 | TSHR (0.33) | ALDH1A1TSHRHSD17B10THRB | |
| SCHEMBL246408 | 0.70 | TSHR (0.39) | ALDH1A1TSHRHSD17B10MAPK1MEN1 | |
| SCHEMBL1048953 | 0.69 | TSHR (0.40) | ALDH1A1TSHRHSD17B10MAPK1MEN1 | |
| SCHEMBL16415640 | 0.67 | CACNA1F (0.35) | HSD17B10 | |
| SCHEMBL246912 | 0.67 | TSHR (0.42) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL28165040 | 0.67 | TSHR (0.36) | ALDH1A1TSHRHSD17B10MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718600-B1 | SYNTHESIS OF SEVERELY STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS FROM A KETENE AND/OR CARBOXYLIC ACID HALIDE AND/OR CARBOXYLIC ACID ANHYDRIDE | EXXONMOBIL RES & ENG CO (US) | 2012-03-28 | — | — | EP | disclosed |
| CN-1922131-B | Synthesis of sterically hindered secondary aminoether alcohols | EXXONMOBIL RES & ENG CO | 2011-04-20 | — | — | CN | disclosed |
| CN-1922134-B | Synthesis of sterically hindered secondary aminoether alcohols | EXXONMOBIL RES & ENG CO | 2010-05-26 | — | — | CN | disclosed |
| EP-1716096-A4 | SYNTHESIS OF STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS | EXXONMOBIL RES & ENG CO (US) | 2008-06-25 | — | — | EP | disclosed |
| US-7351865-B2 | Synthesis of sterically hindered secondary aminoether alcohols from acid anhydride and/or acid halide and sulfur trioxide | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2008-04-01 | — | — | US | disclosed |
| US-20070260092-A1 | Synthesis of Sterically Hindered Secondary Aminoether Alcohols from Acid Anhydride and/or Acid Halide and Sulfur Trioxide | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2007-11-08 | — | — | US | disclosed |
| CN-1922134-A | Synthesis of sterically hindered secondary aminoether alcohols | EXXONMOBIL RES & ENG CO (US) | 2007-02-28 | — | — | CN | disclosed |
| CN-1922131-A | Synthesis of sterically hindered secondary aminoether alcohols | EXXONMOBIL RES & ENG CO (US) | 2007-02-28 | — | — | CN | disclosed |
| CN-1922130-A | Synthesis of sterically hindered secondary aminoether alcohols from carboxylic acid anhydrides and/or carboxylic acid halides and sulfur trioxide | EXXONMOBIL RES & ENG CO (US) | 2007-02-28 | — | — | CN | disclosed |
| CN-1922132-A | Synthesis of severely sterically hindered secondary aminoether alcohols from a ketene and/or carboxylic acid halide and/or carboxylic acid anhydride | EXXONMOBIL RES & ENG CO (US) | 2007-02-28 | — | — | CN | disclosed |
| EP-1716096-A2 | SYNTHESIS OF STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS | ExxonMobil Research and Engineering Company (US) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005081777-A2 | SYNTHESIS OF STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070260092-A1 | Synthesis of Sterically Hindered Secondary Aminoether Alcohols from Acid Anhydride and/or Acid Halide and Sulfur Trioxide | ADH1A, ADH1C, ADH5 | ALDH1A1 50/4885TSHR 486/4885HSD17B10 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.