Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11936455 | 0.80 | CYP1A2 (0.38) | LMNACYP1A2MAPTHTTALDH1A1 | |
| SCHEMBL9256983 | 0.79 | GAA (0.35) | LMNATDP1CYP1A2MAPTHTT | |
| SCHEMBL9680459 | 0.72 | CYP1A2 (0.33) | CYP1A2ALDH1A1 | |
| SCHEMBL22404886 | 0.71 | SMN1; SMN2 (0.37) | LMNATDP1CYP1A2MAPTHTT | |
| SCHEMBL10876748 | 0.71 | HRH4 (0.41) | LMNACYP1A2MAPTHTTPOLB | |
| SCHEMBL3950171 | 0.69 | KDM4E (0.39) | LMNACYP1A2MAPTHTTNPSR1 | |
| SCHEMBL18287434 | 0.68 | ALDH1A1 (0.32) | CYP1A2ALDH1A1 | |
| SCHEMBL8109431 | 0.68 | LMNA (0.50) | LMNATDP1CYP1A2NPSR1POLB | |
| SCHEMBL9432115 | 0.67 | CYP1A2 (0.41) | LMNACYP1A2 | |
| SCHEMBL29079918 | 0.67 | POLB (0.34) | TDP1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723410-A | PLANT GROWTH REGULATORS AND HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
| EP-0546082-B1 | HERBICIDAL PYRROLESULFONYLUREAS | DU PONT (US) | 1996-12-18 | — | — | EP | disclosed |
| US-5585328-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-12-17 | — | — | US | disclosed |
| US-5472933-A | Plant growth regulators | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-12-05 | — | — | US | disclosed |
| EP-0546082-A1 | HERBICIDAL PYRROLESULFONYLUREAS. | DU PONT (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992004319-A1 | HERBICIDAL PYRROLESULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |