SCHEMBL9256983

SCHEMBL9256983

COc1nc(C)nc(OC(N)=O)n1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
LMNA P02545 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NNMT P40261 2/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
POLB P06746 2/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
PARP1 P09874 1/20 0.31
PARP10 Q53GL7 1/20 0.31
PARP2 Q9UGN5 1/20 0.31
PARP4 Q9UKK3 1/20 0.31
TSHR P16473 2/20 0.31
CYP1A2 P05177 1/20 0.30
DYRK1A Q13627 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8528216 0.79 LMNA (0.32) LMNATDP1MAPTHTTNPSR1
SCHEMBL1131131 0.78 GAA (0.47) GAALMNAMAPTHTTTSHR
SCHEMBL8630120 0.74 KIF11 (0.41) LMNACA1CA2PARP1PARP10
SCHEMBL9852781 0.72 KMT2A (0.33) GAANNMTALDH1A1
SCHEMBL9419322 0.72 TSHR (0.50) GAALMNANPSR1PARP1TSHR
SCHEMBL8844371 0.72 GAA (0.47) GAALMNATDP1MAPTHTT
SCHEMBL8109431 0.72 LMNA (0.50) LMNATDP1NNMTNPSR1POLB
SCHEMBL4286264 0.72 GAA (0.46) GAAMAPTHTTNPSR1POLB
SCHEMBL1109013 0.72 NPSR1 (0.42) GAALMNATDP1MAPTHTT
SCHEMBL6628690 0.71 KMT2A (0.51) LMNAMAPTHTTPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5461024-A Herbicides KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-10-24 US disclosed
CN-1077453-A Substituted pyridinesulfonamide compound or its salt prepare its method and the weedicide that contains it ISHIHARA SANGYO KAISHA (JP) 1993-10-20 CN disclosed
WO-1992016525-A1 THIOPHENESULFONYLUREA DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1992-10-01 WO disclosed