Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | CDC25B | P30305 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25C | P30307 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530430 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HPGDMMP8PRNPMAPT | |
| SCHEMBL8529953 | 0.82 | ANPEP (0.36) | ALDH1A1LMNAMMP8PRNPKDM4E | |
| SCHEMBL7050190 | 0.80 | ALDH1A1 (0.35) | ALDH1A1HPGDCDC25BKMT2AMEN1 | |
| SCHEMBL8764856 | 0.79 | PRNP (0.53) | ALDH1A1HPGDKMT2AMEN1LMNA | |
| SCHEMBL7437234 | 0.76 | ALDH1A1 (0.35) | ALDH1A1HPGDCDC25BKMT2AMEN1 | |
| SCHEMBL7437225 | 0.74 | HPGD (0.37) | ALDH1A1HPGDCDC25BKMT2AMEN1 | |
| SCHEMBL7051275 | 0.70 | HPGD (0.39) | ALDH1A1HPGDKMT2AMEN1LMNA | |
| SCHEMBL8528291 | 0.69 | ALDH1A1 (0.39) | ALDH1A1HPGDCDC25BKMT2AMEN1 | |
| SCHEMBL7051265 | 0.69 | ALDH1A1 (0.38) | ALDH1A1HPGDCDC25BKMT2AMEN1 | |
| SCHEMBL7373916 | 0.69 | ALDH1A1 (0.49) | ALDH1A1HPGDCDC25BKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773428-A | BONE DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1998-06-30 | — | — | US | disclosed |