Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529953 | 0.88 | ANPEP (0.36) | ALDH1A1MMP8MAPTNPC1PRNP | |
| SCHEMBL8528294 | 0.82 | ALDH1A1 (0.37) | ALDH1A1HPGDMMP8MAPTSMN1; SMN2 | |
| SCHEMBL8764856 | 0.80 | PRNP (0.53) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL7049701 | 0.77 | ALDH1A1 (0.36) | ALDH1A1HPGDMMP8PIN1MAPT | |
| SCHEMBL7440533 | 0.73 | ALDH1A1 (0.36) | ALDH1A1HPGDMMP8PIN1MAPT | |
| SCHEMBL7440530 | 0.71 | MMP8 (0.39) | ALDH1A1HPGDMMP8PIN1MAPT | |
| SCHEMBL8763176 | 0.69 | HSD17B10 (0.42) | ALDH1A1HPGDPIN1MAPTNPC1 | |
| SCHEMBL11415156 | 0.69 | MMP8 (0.46) | ALDH1A1MMP8PIN1MAPTNPC1 | |
| SCHEMBL8532813 | 0.68 | MMP8 (0.42) | MMP8 | |
| SCHEMBL16732189 | 0.67 | PIN1 (0.47) | ALDH1A1MMP8PIN1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773428-A | BONE DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0807114-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1997-11-19 | — | — | EP | disclosed |