Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530430 | 0.88 | ALDH1A1 (0.38) | ALDH1A1MMP8MAPTPOLBPRNP | |
| SCHEMBL8764856 | 0.82 | PRNP (0.53) | ALDH1A1MAPTPRNPRXFP1LMNA | |
| SCHEMBL8528294 | 0.82 | ALDH1A1 (0.37) | ALDH1A1MMP8MAPTPRNPRXFP1 | |
| SCHEMBL7050118 | 0.79 | ALDH1A1 (0.34) | ANPEPEPHX1GAACYP26A1CYP3A4 | |
| SCHEMBL7438544 | 0.76 | CYP26A1 (0.36) | ANPEPEPHX1GAACYP26A1CYP3A4 | |
| SCHEMBL7438535 | 0.74 | EPHX2 (0.37) | ANPEPEPHX1GAACYP26A1CYP3A4 | |
| SCHEMBL9067733 | 0.72 | CAPN1 (0.44) | ANPEPEPHX1GAACYP3A4CYP2C9 | |
| SCHEMBL1464952 | 0.71 | GAA (0.45) | ANPEPEPHX1GAACYP26A1CYP3A4 | |
| SCHEMBL27041447 | 0.70 | CYP3A4 (0.52) | ANPEPEPHX1GAACYP3A4CYP2C9 | |
| SCHEMBL7050141 | 0.70 | ANPEP (0.39) | ANPEPEPHX1GAACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773428-A | BONE DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1998-06-30 | — | — | US | disclosed |