SCHEMBL8528308

SCHEMBL8528308

N#CCc1ccc(S)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 3/20 0.39
ENPP2 Q13822 1/20 0.38
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
KDM4E B2RXH2 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MMP3 P08254 1/20 0.36
FFAR1 O14842 2/20 0.34
FFAR4 Q5NUL3 1/20 0.34
PTPRC P08575 1/20 0.33
PTPN1 P18031 1/20 0.33
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL435376 0.81 HTT (0.41) ENPP2CYP11B1CYP11B2KDM4ETDP1
SCHEMBL624789 0.77 KIF11 (0.49) ENPP2CYP11B1CYP11B2PTPRCPTPN1
SCHEMBL192429 0.76 MAPT (0.38) ENPP2CYP11B1CYP11B2KDM4ETDP1
SCHEMBL8282785 0.76 DAO (0.41) ENPP2CYP11B1CYP11B2KDM4ETDP1
SCHEMBL14316861 0.76 CYP19A1 (0.45) ENPP2CYP11B1CYP11B2MMP3FFAR1
SCHEMBL24108188 0.76 CYP11B1 (0.58) TRPV4ENPP2CYP11B1CYP11B2
SCHEMBL6679061 0.76 ALDH1A1 (0.45) TRPV4ENPP2CYP11B1CYP11B2KDM4E
SCHEMBL8526639 0.76 ENPP2 (0.38) TRPV4ENPP2KDM4ETDP1MMP3
SCHEMBL502913 0.76 PTPRC (0.41) ENPP2CYP11B1CYP11B2KDM4ETDP1
SCHEMBL8746026 0.76 ENPP2 (0.38) ENPP2KDM4ETDP1MMP3FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0692033-B1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECH GROUP (GB) 1998-03-11 EP claimed
EP-0505198-B1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL IND LTD (JP) 1997-01-02 EP claimed
US-5512451-A MIXTURE OF A AROMATIC DIACYL CYCLIC HYDRAZIDE, PEROXIDASE CATALYST AND OXIDIZER BRITISH TECHNOLOGY GROUP LIMITED (GB) 1996-04-30 US claimed
EP-0692033-A1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BTG INTERNATIONAL LIMITED (GB) 1996-01-17 EP claimed
WO-1994023060-A2 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-10-13 WO claimed
EP-0505198-A1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-23 EP claimed
EP-0692033-B1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECH GROUP (GB) 1998-03-11 EP disclosed
EP-0505198-B1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL IND LTD (JP) 1997-01-02 EP disclosed
US-5512451-A MIXTURE OF A AROMATIC DIACYL CYCLIC HYDRAZIDE, PEROXIDASE CATALYST AND OXIDIZER BRITISH TECHNOLOGY GROUP LIMITED (GB) 1996-04-30 US disclosed
EP-0692033-A1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BTG INTERNATIONAL LIMITED (GB) 1996-01-17 EP disclosed
US-5424194-A Chemiluminescence SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1995-06-13 US disclosed
WO-1994023060-A2 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-10-13 WO disclosed
EP-0505198-A1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-23 EP disclosed