SCHEMBL8526639

SCHEMBL8526639

N#CCc1ccc(S)c(Cl)c1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.38
IDO1 P14902 2/20 0.38
KDM4E B2RXH2 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MMP3 P08254 1/20 0.36
LMNA P02545 2/20 0.36
NPC1 O15118 1/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
TRPV4 Q9HBA0 1/20 0.34
CYP3A4 P08684 1/20 0.32
FFAR1 O14842 1/20 0.32
HPGD P15428 1/20 0.32
PNMT P11086 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP2A6 P11509 1/20 0.31
PTPRC P08575 1/20 0.30
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29609180 0.81 IDO1 (0.52) ENPP2IDO1KDM4ETDP1LMNA
SCHEMBL2308 0.81 IDO1 (0.52) ENPP2IDO1KDM4ETDP1LMNA
SCHEMBL29899625 0.80 CSNK2A1 (0.42) ENPP2IDO1KDM4ETDP1MMP3
SCHEMBL2125469 0.80 CSNK2A1 (0.42) ENPP2IDO1KDM4ETDP1MMP3
SCHEMBL24108441 0.76 TRPV4 (0.52) ENPP2IDO1TRPV4
SCHEMBL15196288 0.76 CA2 (0.52) ENPP2MMP3LMNANPC1MAPT
SCHEMBL4711611 0.76 CYP3A4 (0.61) ENPP2IDO1KDM4ETDP1MMP3
SCHEMBL8528308 0.76 TRPV4 (0.39) ENPP2KDM4ETDP1MMP3TRPV4
SCHEMBL8746026 0.76 ENPP2 (0.38) ENPP2KDM4ETDP1MMP3FFAR1
SCHEMBL7202582 0.76 MAPT (0.43) ENPP2KDM4ETDP1MMP3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0692033-B1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECH GROUP (GB) 1998-03-11 EP claimed
EP-0505198-B1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL IND LTD (JP) 1997-01-02 EP claimed
US-5512451-A MIXTURE OF A AROMATIC DIACYL CYCLIC HYDRAZIDE, PEROXIDASE CATALYST AND OXIDIZER BRITISH TECHNOLOGY GROUP LIMITED (GB) 1996-04-30 US claimed
EP-0692033-A1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BTG INTERNATIONAL LIMITED (GB) 1996-01-17 EP claimed
WO-1994023060-A2 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-10-13 WO claimed
EP-0505198-A1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-23 EP claimed
JP-10313895-A None JP disclosed
EP-2722672-B1 ASSAY METHOD USING MAGNETIC SILICA PARTICLES AND REAGENT FOR SAID ASSAY METHOD SANYO CHEMICAL IND LTD (JP) 2019-02-20 EP disclosed
CN-103597353-B Use assay method and this assay method reagent of magnetic silica particles SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2016-03-02 CN disclosed
US-9157911-B2 Assay method using magnetic silica particles and reagent for said assay method SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2015-10-13 US disclosed
US-20140154713-A1 ASSAY METHOD USING MAGNETIC SILICA PARTICLES AND REAGENT FOR SAID ASSAY METHOD FUJIFILM CORPORATION (JP) 2014-06-05 US disclosed
EP-2722672-A1 ASSAY METHOD USING MAGNETIC SILICA PARTICLES AND REAGENT FOR SAID ASSAY METHOD Sanyo Chemical Industries, Ltd. (JP) 2014-04-23 EP disclosed
CN-103597353-A Assay method using magnetic silica particles and reagent for said assay method SANYO CHEMICAL IND LTD 2014-02-19 CN disclosed
EP-0692033-B1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECH GROUP (GB) 1998-03-11 EP disclosed
EP-0505198-B1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL IND LTD (JP) 1997-01-02 EP disclosed
US-5512451-A MIXTURE OF A AROMATIC DIACYL CYCLIC HYDRAZIDE, PEROXIDASE CATALYST AND OXIDIZER BRITISH TECHNOLOGY GROUP LIMITED (GB) 1996-04-30 US disclosed
EP-0692033-A1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BTG INTERNATIONAL LIMITED (GB) 1996-01-17 EP disclosed
US-5424194-A Chemiluminescence SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1995-06-13 US disclosed
WO-1994023060-A2 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-10-13 WO disclosed
EP-0505198-A1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-23 EP disclosed