Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | CTSG | P08311 | 2/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.33 |
| ▸ | CMA1 | P23946 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532434 | 0.85 | GRM4 (0.40) | PTPN5PTPN1HTTGSK3BPTGDR2 | |
| SCHEMBL8528407 | 0.83 | PTPN1 (0.41) | PTPN5GAAPTPN1 | |
| SCHEMBL8531845 | 0.82 | MEN1 (0.38) | EPHX2MEN1KMT2AL3MBTL1PTPN1 | |
| SCHEMBL8529423 | 0.82 | KIF11 (0.38) | MMP2GAAMAPTPTPN1 | |
| SCHEMBL8532541 | 0.80 | ALDH1A1 (0.33) | MMP2PTPN1 | |
| SCHEMBL8532545 | 0.79 | KIF11 (0.40) | MMP2EPHX2MEN1KMT2AMMP13 | |
| SCHEMBL8530829 | 0.79 | ALDH1A1 (0.40) | KDM4EGAAMAPTL3MBTL1HTT | |
| SCHEMBL8531385 | 0.78 | GRM4 (0.39) | EPHX2MAPTPTPN1PTGDR2 | |
| SCHEMBL8528404 | 0.77 | FDPS (0.38) | PTPN5 | |
| SCHEMBL8529305 | 0.77 | PTPN5 (0.47) | PTPN5MMP2KMT2AMMP13KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752999-B1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | disclosed |