Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 2/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29594461 | 1.00 | GAA (0.65) | GAAL3MBTL1SMN1; SMN2CASP3SENP7 | |
| SCHEMBL10939942 | 0.98 | GAA (0.63) | GAAL3MBTL1SMN1; SMN2CASP3SENP7 | |
| SCHEMBL10667529 | 0.86 | L3MBTL1 (0.47) | GAAL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29878683 | 0.86 | L3MBTL1 (0.47) | GAAL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28874458 | 0.84 | ALDH1A1 (0.56) | GAAL3MBTL1SMN1; SMN2CASP3SENP7 | |
| SCHEMBL14160785 | 0.84 | GAA (0.45) | GAAL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28874293 | 0.83 | L3MBTL1 (0.54) | GAAL3MBTL1SMN1; SMN2CASP3SENP7 | |
| SCHEMBL29878660 | 0.83 | L3MBTL1 (0.54) | GAAL3MBTL1SMN1; SMN2CASP3SENP7 | |
| SCHEMBL7905531 | 0.80 | SMN1; SMN2 (0.70) | GAAL3MBTL1SMN1; SMN2CASP3SENP7 | |
| SCHEMBL2244575 | 0.80 | SMN1; SMN2 (0.70) | GAAL3MBTL1SMN1; SMN2CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686203-A1 | 4-SULFUR SUBSTITUTED PODOPHYLLOTOXIN DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | Tang, Yajie (CN) | 2020-07-29 | — | — | EP | claimed |
| CN-111454308-A | Teniposide derivative and preparation method and application thereof | 湖北工业大学 | 2020-07-28 | — | — | CN | claimed |
| US-20200216462-A1 | 4-Sulfur Substituted Podophyllotoxin Derivative and Preparation Method Therefor and Use Thereof | Tang, YaJie (CN) | 2020-07-09 | — | — | US | claimed |
| US-20200216449-A1 | 4-Sulfur Substituted Podophyllotoxin Derivative and Preparation Method Therefor and Use Thereof | Tang, YaJie (CN) | 2020-07-09 | — | — | US | claimed |
| US-20250155812-A1 | PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN FILM, PHOTOSENSITIVE DRY FILM, AND PATTERN-FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-05-15 | — | — | US | disclosed |
| CN-119987132-A | Photosensitive resin composition, photosensitive resin coating film, photosensitive dry film and pattern forming method | 信越化学工业株式会社 | 2025-05-13 | — | — | CN | disclosed |
| EP-4397502-A1 | ON-MACHINE DEVELOPMENT-TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR MANUFACTURING PRINTING PLATE | FUJIFILM Corporation (JP) | 2024-07-10 | — | — | EP | disclosed |
| US-20240208200-A1 | ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PREPARING PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2024-06-27 | — | — | US | disclosed |
| US-20240110071-A1 | Ultraviolet-Curable Water-Based Ink, Dispersion, Ultraviolet-Curable Water-Based Composition, and Printed Matter | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-04-04 | — | — | US | disclosed |
| EP-4328246-A1 | ULTRAVIOLET-CURABLE AQUEOUS INK, DISPERSION, ULTRAVIOLET-CURABLE AQUEOUS COMPOSITION, AND PRINTED MATTER | Mitsubishi Chemical Corporation (JP) | 2024-02-28 | — | — | EP | disclosed |
| US-11874602-B2 | Lithographic printing plate precursor, method for preparing lithographic printing plate, and lithographic printing method | FUJIFILM CORPORATION (JP) | 2024-01-16 | — | — | US | disclosed |
| CN-115124485-B | Sulfoxide-containing benzoxazole derivative, and preparation method and application thereof | 中国医学科学院药物研究所 | 2023-12-15 | — | — | CN | disclosed |
| WO-2009055357-A1 | DIAZEPANE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-30 | — | — | WO | disclosed |
| US-20080261953-A1 | Compounds, Compositions and Methods of Inhibiting Alpha-Synuclein Toxicity | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2008-10-23 | — | — | US | disclosed |
| US-20080261953-A1 | Compounds, Compositions and Methods of Inhibiting Alpha-Synuclein Toxicity | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2008-10-23 | — | — | US | disclosed |
| US-20080261953-A1 | Compounds, Compositions and Methods of Inhibiting Alpha-Synuclein Toxicity | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2008-10-23 | — | — | US | disclosed |
| US-6288236-B1 | PREVENTIVE AND THERAPEUTIC MEDICAMENT FOR HYPERLIPEMIA OR ARTERIAL SCLEROSIS. | FUJI PHOTO FILM CO., LTD. (JP) | 2001-09-11 | — | — | US | disclosed |
| US-6174907-B1 | THERAPY AND PROPHYLAXIS OF HYPERLIPEMIA OR ARTERIAL SCLEROSIS; AS ADDITIVE OF A SILVER HALIDE PHOTOSENSITIVE MATERIAL, LIQUID CRYSTAL MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 2001-01-16 | — | — | US | disclosed |
| US-5998456-A | ANTILIPEMIC AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0849259-A1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1998-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261953-A1 | Compounds, Compositions and Methods of Inhibiting Alpha-Synuclein Toxicity | SNCA, PARK7, HTT | GAA 62/4885L3MBTL1 244/4885SMN1; SMN2 41/4885 |
| US-20200216462-A1 | 4-Sulfur Substituted Podophyllotoxin Derivative and Preparation Method Therefor and Use Thereof | WEE1, WEE2, DHFR | GAA 4521/4885L3MBTL1 350/4885SMN1; SMN2 4767/4885 |
| US-20200216449-A1 | 4-Sulfur Substituted Podophyllotoxin Derivative and Preparation Method Therefor and Use Thereof | TPMT, WEE1, DHFR | GAA 4636/4885L3MBTL1 343/4885SMN1; SMN2 4687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.