Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13119220 | 0.84 | KCNJ1 (0.36) | HCAR3APLNRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL198067 | 0.84 | ALDH1A1 (0.52) | HCAR3KDM4EALDH1A1HSD17B10ALOX15 | |
| SCHEMBL1435924 | 0.82 | NAPRT (0.36) | HCAR3APLNRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL24065698 | 0.82 | HCAR3 (0.34) | HCAR3APLNRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL14865432 | 0.82 | NNMT (0.45) | VNN1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL30445356 | 0.79 | BAZ2B (0.45) | HTTSMN1; SMN2HPGD | |
| SCHEMBL22387737 | 0.79 | HDAC6 (0.57) | — | |
| SCHEMBL1435071 | 0.79 | MAPK1 (0.52) | KDM4EALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL26421531 | 0.79 | PDE9A (0.41) | HCAR3APLNRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL24925816 | 0.77 | KDM4E (0.42) | HCAR3KDM4EALDH1A1HCAR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763640-A | OXIMINOMETHYLPHENYL DERIVATIVES | ZENECA LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| EP-0370629-B2 | Fungicides | ZENECA LTD (GB) | 1998-01-07 | — | — | EP | disclosed |
| US-5631253-A | FUNGICIDES, INSECTICIDES AND MITICIDES USING METHYLOXIME PHENYLPROPENOIC ACID | ZENECA LIMITED (GB) | 1997-05-20 | — | — | US | disclosed |
| US-5432197-A | Insecticidal, miticidal | ZENECA LIMITED (GB) | 1995-07-11 | — | — | US | disclosed |
| US-5371084-A | Insecticides and miticides | ZENECA LIMITED (GB) | 1994-12-06 | — | — | US | disclosed |
| EP-0506149-A2 | Fungicides | ZENECA LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |
| US-5055471-A | FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-08 | — | — | US | disclosed |
| EP-0370629-A1 | Fungicides | ZENECA LIMITED (GB) | 1990-05-30 | — | — | EP | disclosed |