Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7224446 | 0.82 | HPGD (0.46) | JAK2JAK1TYK2ALDH1A1POLB | |
| SCHEMBL6429960 | 0.81 | POLB (0.52) | L3MBTL1LMNAALDH1A1POLBGAA | |
| SCHEMBL8527199 | 0.77 | ALDH1A1 (0.36) | JAK2JAK1TYK2L3MBTL1LMNA | |
| SCHEMBL7217595 | 0.77 | ALDH1A1 (0.38) | JAK2JAK1TYK2L3MBTL1LMNA | |
| SCHEMBL7845245 | 0.74 | POLB (0.46) | L3MBTL1ALDH1A1POLBHPGDRAB9A | |
| SCHEMBL7846596 | 0.72 | HPGD (0.45) | JAK2JAK1TYK2ALDH1A1POLB | |
| SCHEMBL7854326 | 0.72 | HPGD (0.57) | L3MBTL1LMNAALDH1A1HPGD | |
| SCHEMBL7853870 | 0.72 | HPGD (0.51) | ALDH1A1HPGDGLAPKM | |
| SCHEMBL7219457 | 0.72 | HPGD (0.44) | ALDH1A1POLBHPGDRAB9AGLA | |
| SCHEMBL6428445 | 0.72 | ALDH1A1 (0.47) | LMNAALDH1A1GAAFEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849723-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5834447-A | THIOPHENE DERIVATIVES | MONSANTO COMPANY (US) | 1998-11-10 | — | — | US | disclosed |
| US-5811411-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5705513-A | HETEROCYCLIC FUNGICIDES WITH PYRIDINE OR FURAN RINGS | MONSANTO COMPANY (US) | 1998-01-06 | — | — | US | disclosed |
| US-5693667-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1997-12-02 | — | — | US | disclosed |