Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8529232 | 0.96 | LTA4H (0.50) | LTA4HCHRNA7CHRNB4CHRNA3CHRNB2 | |
| Hydrochloric Acid SCHEMBL11327340 | 0.84 | ALDH1A1 (0.54) | LTA4HCHRNA7CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL10455942 | 0.82 | ALDH1A1 (0.55) | LTA4HCHRNA7CHRNB4CHRNA3CHRNB2 | |
| Hydrochloric Acid SCHEMBL7263491 | 0.82 | KDM4E (0.58) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL425185 | 0.82 | KDM4E (0.58) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL80718 | 0.82 | KDM4E (0.58) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL27652915 | 0.81 | KDM4E (0.65) | LTA4HTSHRFFAR1SRD5A2 | |
| Bromide SCHEMBL11337434 | 0.81 | ALDH1A1 (0.54) | LTA4HCHRNA7CHRNB4CHRNA3CHRNB2 | |
| Hydrochloric Acid SCHEMBL9653571 | 0.80 | KDM4E (0.56) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Ammonia Solution, Strong SCHEMBL10810468 | 0.80 | KDM4E (0.56) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609455-B1 | PROCESS FOR PRODUCING CRESOLS | SUMITOMO CHEMICAL CO (JP) | 1998-03-11 | — | — | EP | disclosed |
| US-5600026-A | PREVENTING THE FORMATION OF FORMALDEHYDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-04 | — | — | US | disclosed |
| EP-0609455-A1 | PROCESS FOR PRODUCING CRESOLS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-08-10 | — | — | EP | disclosed |
| US-5166451-A | Peroxide mixture and quaternary ammonium salt for reducing the content of primary hydroperoxides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-11-24 | — | — | US | disclosed |
| US-4172782-A | ORGANIC QUATERNARY AMMONIUM SALT USED IN ALKULATION OF BENZYLNITRILE WITH AN ORGANIC HALIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-10-30 | — | — | US | disclosed |