Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5117671 | 0.81 | ALDH1A1 (0.44) | KMT2AMEN1NPC1RAB9AS1PR4 | |
| SCHEMBL540885 | 0.81 | ALDH1A1 (0.52) | KMT2AMEN1NPC1RAB9AS1PR4 | |
| SCHEMBL2125795 | 0.81 | KMT2A (0.43) | KMT2AMEN1NPC1RAB9AS1PR4 | |
| SCHEMBL10565139 | 0.80 | KMT2A (0.60) | KMT2AMEN1NPC1RAB9AS1PR4 | |
| SCHEMBL29903448 | 0.79 | KMT2A (0.41) | KMT2AMEN1NPC1RAB9AS1PR4 | |
| SCHEMBL3167072 | 0.79 | KMT2A (0.41) | KMT2AMEN1NPC1RAB9AS1PR4 | |
| SCHEMBL27873051 | 0.79 | KMT2A (0.41) | KMT2AMEN1NPC1RAB9AS1PR4 | |
| SCHEMBL7116983 | 0.77 | KMT2A (0.50) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL8601536 | 0.77 | PDE4A (0.41) | KMT2AMEN1NPC1RAB9AS1PR4 | |
| SCHEMBL4666888 | 0.77 | NPC1 (0.48) | KMT2AMEN1NPC1RAB9AS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5969077-A | Polysiloxanes containing heterocyclic functions, their preparation and use | WACKER-CHEMIE GMBH (DE) | 1999-10-19 | — | — | US | disclosed |