Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 2/20 | 0.49 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.49 |
| ▸ | CPT2 | P23786 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | SPR | P35270 | 1/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2686872 | 0.83 | SPR (0.62) | AKR1C3KDM4ENQO2MTNR1AMTNR1B | |
| SCHEMBL2686296 | 0.82 | MTNR1A (0.65) | AKR1C3NQO2MTNR1AMTNR1B | |
| SCHEMBL20604920 | 0.82 | KDM4E (0.47) | AKR1C3KDM4ENQO2MTNR1AMTNR1B | |
| SCHEMBL4012453 | 0.79 | KDM4E (0.65) | KDM4ES1PR2 | |
| SCHEMBL31498840 | 0.79 | KDM4E (0.65) | KDM4ES1PR2 | |
| SCHEMBL8536461 | 0.78 | PLA2G4A (0.61) | CPT1ACPT1BCPT2 | |
| SCHEMBL2807415 | 0.78 | NR4A2 (0.46) | CPT1ACPT1BCPT2KDM4E | |
| SCHEMBL2804273 | 0.77 | NR4A2 (0.45) | KDM4E | |
| SCHEMBL3352657 | 0.77 | HPGD (0.49) | CPT1ACPT1BCPT2KDM4ENQO2 | |
| SCHEMBL2804408 | 0.76 | PLA2G4A (0.46) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489547-B1 | A process for the preparation of a 3-alkylated indole, intermediates, and a process for the preparation of a derivative thereof | ZENECA LTD (GB) | 1998-07-29 | — | — | EP | disclosed |
| US-5280125-A | Chemical process for the preparation of 3-alkylated indole | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-18 | — | — | US | disclosed |
| EP-0489547-A1 | A process for the preparation of a 3-alkylated indole, intermediates, and a process for the preparation of a derivative thereof | ZENECA LIMITED (GB) | 1992-06-10 | — | — | EP | disclosed |