Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.43 |
| ▸ | CTSK | P43235 | 13/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529631 | 1.00 | CTSS (0.43) | CTSSCTSKCTSLCTSBTACR1 | |
| SCHEMBL8422169 | 0.91 | CTSS (0.45) | CTSSCTSKCTSLCTSB | |
| SCHEMBL8422170 | 0.91 | CTSS (0.45) | CTSSCTSKCTSLCTSB | |
| SCHEMBL8529714 | 0.85 | LMNA (0.47) | CTSSCTSKCTSLCTSB | |
| SCHEMBL8529711 | 0.85 | LMNA (0.47) | CTSSCTSKCTSLCTSB | |
| SCHEMBL8423620 | 0.84 | CTSK (0.43) | CTSSCTSKCTSLCTSBTACR1 | |
| SCHEMBL8587115 | 0.83 | CTSS (0.37) | CTSSCTSKCTSLCTSBTACR1 | |
| SCHEMBL8526634 | 0.82 | CTSS (0.36) | CTSSCTSKCTSLCTSBTACR1 | |
| SCHEMBL8422157 | 0.81 | CTSS (0.45) | CTSSCTSKCTSLCTSBTACR1 | |
| SCHEMBL8530056 | 0.81 | CTSS (0.45) | CTSSCTSKCTSLCTSBTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705257-B1 | AMINOACID DERIVATIVES AS NO SYNTHASE INHIBITORS | WELLCOME FOUND (GB) | 1998-03-11 | — | — | EP | disclosed |