Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | RBP4 | P02753 | 2/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430935 | 0.79 | TACR1 (0.50) | HTR2CTACR1TP53CYP1A2CYP3A4 | |
| SCHEMBL5790938 | 0.71 | GAA (0.43) | HTR2CHTR2AHTR2BRBP4GAA | |
| SCHEMBL2908098 | 0.70 | KDM1A (0.37) | TACR1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5968438 | 0.69 | GAA (0.44) | HTR2CHTR2BRBP4TACR1GAA | |
| SCHEMBL15670008 | 0.68 | HTR2C (0.49) | HTR2CHTR2BRBP4GAATDP1 | |
| SCHEMBL27743375 | 0.67 | POLB (0.40) | HTR2BTSHR | |
| SCHEMBL2913724 | 0.66 | POLB (0.42) | HTR2BTDP1TSHRMEN1KMT2A | |
| SCHEMBL2908423 | 0.66 | KMT2A (0.40) | GAATDP1TSHRMEN1KMT2A | |
| SCHEMBL28490903 | 0.66 | ALDH1A1 (0.41) | HTR2BPRCPGAACYP1A2CYP2D6 | |
| SCHEMBL16226110 | 0.65 | CHRNA7 (0.52) | PRCPTACR1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795894-A | TREATMENT OF ASTHMA AND BRONCHOSPASM | SCHERING CORPORATION (US) | 1998-08-18 | — | — | US | disclosed |