Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 5/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27743375 | 0.84 | POLB (0.40) | POLBRIPK1P2RX7CHRNB2CHRNB4 | |
| SCHEMBL2913724 | 0.82 | POLB (0.42) | POLBRIPK1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2915821 | 0.80 | ADRB1 (0.40) | POLBADRB1ALDH1A1MEN1MAPT | |
| SCHEMBL2908423 | 0.79 | KMT2A (0.40) | POLBRIPK1ADRB1ALDH1A1TSHR | |
| SCHEMBL2911565 | 0.77 | SLC18A3 (0.39) | POLBRIPK1ALDH1A1TSHRMEN1 | |
| SCHEMBL3926373 | 0.73 | RPS6KB1 (0.39) | POLB | |
| SCHEMBL8430935 | 0.70 | TACR1 (0.50) | TACR1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8530408 | 0.70 | HTR2C (0.44) | TACR1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3923843 | 0.69 | RPS6KB1 (0.38) | ALDH1A1KMT2A | |
| Formamide SCHEMBL28989148 | 0.69 | HTR1A (0.42) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472901-B | Stereoselective synthesis of -1-methyl-3-phenylpiperazine | ORGANON NV | 2011-08-03 | — | — | CN | disclosed |
| EP-2038260-B1 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE | ORGANON NV (NL) | 2010-09-01 | — | — | EP | disclosed |
| US-20100036126-A1 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE | N.V. ORGANON (NL) | 2010-02-11 | — | — | US | disclosed |
| CN-101472901-A | Stereoselective synthesis of -1-methyl-3-phenylpiperazine | ORGANON NV (NL) | 2009-07-01 | — | — | CN | disclosed |
| EP-2038260-A1 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE | N.V. Organon (NL) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007144409-A1 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE | N.V. ORGANON (NL) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036126-A1 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE | THOP1, PRSS1, DPEP1 | KDM1A 278/4885POLB 613/4885RIPK1 1564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.