Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27743375 | 0.89 | POLB (0.40) | POLBCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL3926373 | 0.88 | RPS6KB1 (0.39) | POLBTDP1SLC6A2SLC6A3OPRK1 | |
| SCHEMBL2915821 | 0.85 | ADRB1 (0.40) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2908423 | 0.84 | KMT2A (0.40) | POLBTDP1SLC18A3ALDH1A1TSHR | |
| SCHEMBL2908098 | 0.82 | KDM1A (0.37) | POLBCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL2911565 | 0.81 | SLC18A3 (0.39) | POLBTDP1SLC18A3ALDH1A1TSHR | |
| SCHEMBL8278741 | 0.74 | SLC6A2 (0.48) | POLBSLC18A3CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3923843 | 0.73 | RPS6KB1 (0.38) | SLC18A3ALDH1A1KMT2ALMNASLC6A2 | |
| Formamide SCHEMBL28989148 | 0.73 | HTR1A (0.42) | TDP1SLC18A3CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL24203568 | 0.72 | TSHR (0.41) | POLBTDP1SLC18A3GBA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472901-B | Stereoselective synthesis of -1-methyl-3-phenylpiperazine | ORGANON NV | 2011-08-03 | — | — | CN | disclosed |
| EP-2038260-B1 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE | ORGANON NV (NL) | 2010-09-01 | — | — | EP | disclosed |
| US-20100036126-A1 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE | N.V. ORGANON (NL) | 2010-02-11 | — | — | US | disclosed |
| CN-101472901-A | Stereoselective synthesis of -1-methyl-3-phenylpiperazine | ORGANON NV (NL) | 2009-07-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036126-A1 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE | THOP1, PRSS1, DPEP1 | POLB 613/4885TDP1 718/4885SLC18A3 4523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.