Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14931991 | 1.00 | HTR2C (0.46) | HTR2CL3MBTL1KDM1ALTA4HMEN1 | |
| SCHEMBL7480391 | 0.80 | PRCP (0.38) | HTR2CKDM1ALTA4H | |
| SCHEMBL8533494 | 0.80 | PRCP (0.38) | HTR2CKDM1ALTA4H | |
| SCHEMBL8533774 | 0.77 | MAPT (0.42) | HTR2CKDM1AMAPTCYP1A2CYP3A4 | |
| SCHEMBL6227686 | 0.76 | SLC18A3 (0.38) | GAATACR1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL472003 | 0.76 | SLC18A3 (0.38) | GAATACR1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8900994 | 0.72 | ADRA2C (0.44) | KDM1AMEN1KMT2AALDH1A1 | |
| SCHEMBL8531757 | 0.72 | KDM1A (0.37) | HTR2CKDM1A | |
| SCHEMBL3597818 | 0.71 | HTR2C (0.53) | HTR2CL3MBTL1KDM1ALTA4HMEN1 | |
| SCHEMBL6177442 | 0.71 | HTR2C (0.53) | HTR2CL3MBTL1KDM1ALTA4HMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843966-A | Piperidine derivatives | GLAXO GROUP LIMITED (GB) | 1998-12-01 | — | — | US | disclosed |
| US-5703240-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS; GASTROINTESTINAL DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |