Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LIG1 | P18858 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480391 | 1.00 | PRCP (0.38) | PRCPATMKDM1ATDP1LTA4H | |
| SCHEMBL8533774 | 0.81 | MAPT (0.42) | PRCPATMKDM1ATDP1HTR2A | |
| SCHEMBL14931991 | 0.80 | HTR2C (0.46) | KDM1ALTA4HHTR2C | |
| SCHEMBL8531757 | 0.80 | KDM1A (0.37) | KDM1ASLC6A2HTR2AHTR2CSLC6A4 | |
| SCHEMBL8530413 | 0.80 | HTR2C (0.46) | KDM1ALTA4HHTR2C | |
| SCHEMBL472003 | 0.80 | SLC18A3 (0.38) | PRCPSLC6A2HTR2BSLC6A3 | |
| SCHEMBL6227686 | 0.80 | SLC18A3 (0.38) | PRCPSLC6A2HTR2BSLC6A3 | |
| SCHEMBL8530249 | 0.79 | HTR2A (0.37) | KDM1AHTR2AHTR2CHTR2B | |
| SCHEMBL8530406 | 0.76 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6368619 | 0.72 | CHRNB2 (0.50) | PRCPATMKDM1ATDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843966-A | Piperidine derivatives | GLAXO GROUP LIMITED (GB) | 1998-12-01 | — | — | US | disclosed |
| US-5703240-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS; GASTROINTESTINAL DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |