Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CBFB | Q13951 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535564 | 0.92 | MAT2A (0.66) | MAT2AKDM4ECYP1A1CYP1A2CYP1B1 | |
| SCHEMBL8536444 | 0.91 | MAT2A (0.64) | MAT2AKDM4EKIF11MAPK13MAPK12 | |
| SCHEMBL8533188 | 0.89 | MAT2A (0.62) | MAT2AKIF11TRPA1ACP1LMNA | |
| SCHEMBL8536602 | 0.89 | MAT2A (0.62) | MAT2AKDM4EKIF11CYP1A2TRPA1 | |
| SCHEMBL18987275 | 0.88 | MAT2A (0.69) | MAT2AKDM4EKIF11PDE5ACYP1A1 | |
| SCHEMBL8537912 | 0.88 | MAT2A (0.59) | MAT2AKDM4EKIF11ACP1KMT2A | |
| SCHEMBL8535958 | 0.87 | MAT2A (0.59) | MAT2AKDM4EKIF11TRPA1ACP1 | |
| SCHEMBL8537832 | 0.85 | MAT2A (0.69) | MAT2AKDM4EKIF11MAPK13MAPK12 | |
| SCHEMBL8537111 | 0.83 | MAT2A (0.55) | MAT2AKDM4EACP1MEN1KMT2A | |
| SCHEMBL8533063 | 0.83 | MAT2A (0.55) | MAT2AKDM4EKIF11CYP1A2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | claimed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |