Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.69 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530848 | 0.85 | MAT2A (0.77) | MAT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL18987275 | 0.83 | MAT2A (0.69) | MAT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8538579 | 0.79 | MAT2A (0.61) | MAT2ACYP19A1 | |
| SCHEMBL30692180 | 0.77 | MAT2A (0.58) | MAT2AKDM4EALDH1A1HPGDMAPK13 | |
| SCHEMBL26924860 | 0.77 | MAT2A (0.58) | MAT2AKDM4EALDH1A1HPGDMAPK13 | |
| SCHEMBL8535564 | 0.77 | MAT2A (0.66) | MAT2AKDM4EALDH1A1HPGDALOX5 | |
| SCHEMBL8515371 | 0.77 | MAT2A (0.56) | MAT2AKDM4EALDH1A1HPGDKIF11 | |
| SCHEMBL8536444 | 0.76 | MAT2A (0.64) | MAT2AKDM4EALDH1A1MAPK13MAPK12 | |
| SCHEMBL20983234 | 0.75 | MAT2A (0.58) | MAT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8537070 | 0.74 | MAT2A (0.57) | MAT2AKDM4EHSD17B10KIF11CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | claimed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |