SCHEMBL8532004

SCHEMBL8532004

CCCCCCCCCCC/C(=N\OC(=O)c1ccccc1)OCC

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.49
CES1 P23141 3/20 0.49
LMNA P02545 2/20 0.45
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
NAAA Q02083 1/20 0.41
KMT2A Q03164 1/20 0.41
PTPN1 P18031 1/20 0.41
ACP1 P24666 1/20 0.41
CDC25B P30305 1/20 0.41
CDK5 Q00535 2/20 0.41
CDK5R1 Q15078 2/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
GAA P10253 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10658582 1.00 CES2 (0.49) CES2CES1LMNAALDH1A1TSHR
SCHEMBL8532009 1.00 CES2 (0.49) CES2CES1LMNAALDH1A1TSHR
SCHEMBL11100077 0.87 LMNA (0.38) LMNAALDH1A1SMN1; SMN2KMT2ACDK5
SCHEMBL11250495 0.83 LMNA (0.49) LMNAALDH1A1TSHRSMN1; SMN2KMT2A
Ethyl Benzoate SCHEMBL27281972 0.79 LMNA (0.65) CES2CES1LMNAALDH1A1TSHR
SCHEMBL27893429 0.78 CES2 (0.49) CES2CES1LMNAALDH1A1SMN1; SMN2
SCHEMBL28249199 0.78 CES2 (0.49) CES2CES1LMNAALDH1A1SMN1; SMN2
SCHEMBL28907502 0.78 CES2 (0.49) CES2CES1LMNAALDH1A1SMN1; SMN2
SCHEMBL2111260 0.78 CES2 (0.56) CES2CES1LMNASMN1; SMN2KMT2A
SCHEMBL2111257 0.78 CES2 (0.56) CES2CES1LMNASMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1020247-A None JP disclosed
EP-0873198-A4 IMPROVED CONDUCTIVE WIRE COATING UNION CAMP CORP (US) 1998-12-16 EP disclosed
EP-0873198-A1 IMPROVED CONDUCTIVE WIRE COATING UNION CAMP CORPORATION (US) 1998-10-28 EP disclosed
US-5786086-A COATING THE CONDUCTIVE WIRE WITH AN INSULATING MATERIAL COMPRISING SOLVENT-FREE CURABLE ACRYLATED MODIFIED AMINOAMIDE RESIN, CURING TO PROVIDE INSULATED WIRE WITH SMOOTH, TACK-FREE SURFACE UNION CAMP CORPORATION (US) 1998-07-28 US disclosed
WO-1997024191-A1 IMPROVED CONDUCTIVE WIRE COATING UNION CAMP CORPORATION (US) 1997-07-10 WO disclosed
JP-S6420247-A SEMICONDUCTIVE COMPOSITION AND METHOD FOR FORMING SEMICONDUCTIVE LAYER OF POWER CABLE FUJIKURA LTD 1989-01-24 JP disclosed