SCHEMBL8532142

SCHEMBL8532142

Cc1cc[c]c(-c2ccc(Oc3ccccc3)cc2)c1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.43
LTA4H P09960 6/20 0.41
ALDH1A1 P00352 1/20 0.41
HTT P42858 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
TSHR P16473 1/20 0.40
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
NR1H2 P55055 1/20 0.37
BAX Q07812 1/20 0.37
MAOA P21397 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
DHODH Q02127 1/20 0.36
SCN4A P35499 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8529939 0.84 GSTP1 (0.47) GSTP1LTA4HALDH1A1SMN1; SMN2TSHR
SCHEMBL4125762 0.84 MAOB (0.37) ALDH1A1HTTSMN1; SMN2TSHRNPC1
SCHEMBL193137 0.84 MAOB (0.39) ALDH1A1HTTSMN1; SMN2TSHRNPC1
SCHEMBL8531326 0.82 LTA4H (0.53) GSTP1LTA4HALDH1A1HTTSMN1; SMN2
SCHEMBL7703865 0.81 GSTP1 (0.44) GSTP1LTA4HTSHRNPC1RAB9A
SCHEMBL7661455 0.81 ACHE (0.45) SMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL10871646 0.81 GSTP1 (0.41) GSTP1LTA4HALDH1A1HTTTSHR
SCHEMBL8531642 0.80 GSTP1 (0.43) GSTP1LTA4HSMN1; SMN2TSHRNPC1
SCHEMBL7703136 0.79 LTA4H (0.46) GSTP1LTA4HALDH1A1SMN1; SMN2TSHR
SCHEMBL102139 0.78 TDP1 (0.36) ALDH1A1HTTSMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5749925-A Dyeing or printing process with new and known cationic 4,5-dihydro-iH-1,2,3-triazolium compounds as dyestuffs and new cationic 4,5-dihydro-1H-1,2,3-triazolium compounds BAYER AKTIENGESELLSCHAFT (DE) 1998-05-12 US disclosed
US-5356908-A Agriculture E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-10-18 US disclosed
US-5223523-A Agriculture E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-29 US disclosed
US-4957933-A Fungicidal oxazolidinones E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-18 US disclosed