Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | BAX | Q07812 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FABP1 | P07148 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529939 | 0.94 | GSTP1 (0.47) | LTA4HTSHRMAOBGSTP1AKR1C3 | |
| SCHEMBL8315326 | 0.93 | MAOB (0.44) | LTA4HTSHRMAOBGSTP1AKR1C3 | |
| SCHEMBL16719650 | 0.88 | NOTUM (0.39) | LTA4HTSHRMAOBGSTP1SMN1; SMN2 | |
| SCHEMBL16719443 | 0.87 | PGR (0.40) | LTA4HTSHRMAOBGSTP1AKR1C3 | |
| SCHEMBL10965408 | 0.85 | GSTP1 (0.37) | LTA4HTSHRMAOBGSTP1AKR1C3 | |
| SCHEMBL16719819 | 0.85 | LTA4H (0.42) | LTA4HTSHRMAOBAKR1C3NR1H2 | |
| SCHEMBL8531326 | 0.84 | LTA4H (0.53) | LTA4HTSHRGSTP1SMN1; SMN2CYP1A2 | |
| SCHEMBL7795502 | 0.84 | KIF11 (0.44) | LTA4HTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6848644 | 0.84 | KIF11 (0.44) | LTA4HTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7703865 | 0.84 | GSTP1 (0.44) | LTA4HTSHRGSTP1MAOANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |
| EP-1216285-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | Ciba SC Holding AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019939-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-22 | — | — | WO | disclosed |
| EP-1028945-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS ANTI-INFLAMMATORY AGENTS | Amgen Inc. (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999024404-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS ANTI-INFLAMMATORY AGENTS | AMGEN INC. (US) | 1999-05-20 | — | — | WO | disclosed |