Bromide

Bromide

SCHEMBL8532437

Br.C=CCC(CN(C)C)=C(C)C(N)=O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170138 0.82 TDP1 (0.38)
SCHEMBL3281499 0.79 PAOX (0.33)
SCHEMBL1635822 0.74 TDP1 (0.38)
SCHEMBL1201121 0.74 TDP1 (0.38)
SCHEMBL5683864 0.73 TDP1 (0.33)
SCHEMBL18660282 0.73 TDP1 (0.33)
SCHEMBL905535 0.73 TSHR (0.32)
SCHEMBL25416543 0.70 TDP1 (0.38)
SCHEMBL500684 0.69 ALDH1A1 (0.38)
SCHEMBL2448134 0.69 ALDH1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10337282-B2 Methods and compositions for reducing water production in fractures or voids in subterranean formations HALLIBURTON ENERGY SERVICES, INC. (US) 2019-07-02 US disclosed
US-20180022982-A1 METHODS AND COMPOSITIONS FOR REDUCING WATER PRODUCTION IN FRACTURES OR VOIDS IN SUBTERRANEAN FORMATIONS HALLIBURTON ENERGY SERVICES, INC. (US) 2018-01-25 US disclosed
WO-2016153519-A1 METHODS AND COMPOSITIONS FOR REDUCING WATER PRODUCTION IN FRACTURES OR VOIDS IN SUBTERRANEAN FORMATIONS HALLIBURTON ENERGY SERVICES, INC. (US) 2016-09-29 WO disclosed
US-8991495-B2 Methods for protecting a hydrocarbon-producing zone of a subterranean formation using a relative permeability modifier HALLIBURTON ENERGY SERVICES, INC. (US) 2015-03-31 US disclosed
WO-2013173600-A2 METHODS FOR PROTECTING A HYDROCARBON-PRODUCING ZONE OF A SUBTERRANEAN FORMATION USING A RELATIVE PERMEABILITY MODIFIER HALLIBURTON ENERGY SERVICES, INC. (US) 2013-11-21 WO disclosed
US-20130306314-A1 Methods for Protecting a Hydrocarbon-Producing Zone of a Subterranean Formation Using a Relative Permeability Modifier HALLIBURTON ENERGY SERVICES, INC. (US) 2013-11-21 US disclosed
EP-2646522-A1 COMPOSITIONS AND METHODS RELATING TO THE STABILIZATION OF HYDROPHOBICALLY MODIFIED HYDROPHILIC POLYMER TREATMENT FLUIDS UNDER ALKALINE CONDITIONS Halliburton Energy Services, Inc. (US) 2013-10-09 EP disclosed
US-8470746-B2 Methods relating to the stabilization of hydrophobically modified hydrophilic polymer treatment fluids under alkaline conditions HALLIBURTON ENERGY SERVICES, INC. (US) 2013-06-25 US disclosed
WO-2013068707-A1 COMPOSITIONS AND METHODS RELATING TO THE STABILIZATION OF HYDROPHOBICALLY MODIFIED HYDROPHILIC POLYMER TREATMENT FLUIDS UNDER ALKALINE CONDITIONS HALLIBURTON ENERGY SERVICES, INC (US) 2013-05-16 WO disclosed
US-20120135895-A1 Compositions and Methods Relating to the Stabilization of Hydrophobically Modified Hydrophilic Polymer Treatment Fluids Under Alkaline Conditions HALLIBURTON ENERGY SERVICES, INC. (US) 2012-05-31 US disclosed