SCHEMBL905535

SCHEMBL905535

C=CCC(CC=C)=C(C)C(N)=O.C=CCNCC=C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170138 0.88 TDP1 (0.38) TSHRALDH1A1TDP1
SCHEMBL6675863 0.74 TSHR (0.41) TSHRALDH1A1SMN1; SMN2MAPT
SCHEMBL3281499 0.74 PAOX (0.33) ALDH1A1TDP1
Bromide SCHEMBL8532437 0.73
Urea SCHEMBL27483216 0.73 ALDH1A1 (0.44) TSHRALDH1A1SMN1; SMN2MAPTTDP1
Acetic Acid SCHEMBL28451525 0.73 SMN1; SMN2 (0.41) TSHRALDH1A1SMN1; SMN2MAPT
Acetic Acid SCHEMBL968509 0.73 SMN1; SMN2 (0.41) TSHRALDH1A1SMN1; SMN2MAPT
SCHEMBL25416543 0.71 TDP1 (0.38) TSHRALDH1A1TDP1
SCHEMBL1635822 0.71 TDP1 (0.38) TSHRALDH1A1TDP1
SCHEMBL1201121 0.71 TDP1 (0.38) TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150174735-A1 HIGH POROSITY ABRASIVE ARTICLES AND METHODS OF MANUFACTURING SAME SAINT GOBAIN ABRASIVES INC (US) 2015-06-25 US disclosed
US-8986407-B2 High porosity abrasive articles and methods of manufacturing same SAINT-GOBAIN ABRASIVES, INC. (US) 2015-03-24 US disclosed
EP-2276820-A2 HIGH POROSITY ABRASIVE ARTICLES AND METHODS OF MANUFACTURING SAME Saint-Gobain Abrasives, Inc. (US) 2011-01-26 EP disclosed
WO-2009128982-A2 HIGH POROSITY ABRASIVE ARTICLES AND METHODS OF MANUFACTURING SAME SAINT-GOBAIN ABRASIVES, INC. (US) 2009-10-22 WO disclosed
US-20090264050-A1 HIGH POROSITY ABRASIVE ARTICLES AND METHODS OF MANUFACTURING SAME SAINT-GOBAIN ABRASIVES, INC. (US) 2009-10-22 US disclosed
EP-0993337-B1 HYDROPHILIC POLYMERIC MATERIAL AND METHOD OF PREPARATION SUNSTORM RES CORP (US) 2004-04-14 EP disclosed
US-6218440-B1 Hydrophilic polymeric material and method of preparation BIOPORE CORPORATION 2001-04-17 US disclosed
EP-0993337-A1 HYDROPHILIC POLYMERIC MATERIAL AND METHOD OF PREPARATION BIOPORE CORPORATION (US) 2000-04-19 EP disclosed
US-6048908-A POROUS CROSSLINKED ADDITION POLYMER MICROBEADS FOR ABSORBERS OR CARRIERS BIOPORE CORPORATION (US) 2000-04-11 US disclosed
WO-1999000187-A1 HYDROPHILIC POLYMERIC MATERIAL AND METHOD OF PREPARATION BIOPORE CORPORATION (US) 1999-01-07 WO disclosed