Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 7/20 | 0.39 |
| ▸ | PLAT | P00750 | 6/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.39 |
| ▸ | F7 | P08709 | 4/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | HEXA | P06865 | 1/20 | 0.35 |
| ▸ | HEXB | P07686 | 1/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832583 | 0.84 | BCAT2 (0.50) | PLAUPLATKLKB1PRSS1PRSS2 | |
| SCHEMBL7862971 | 0.83 | SLC6A4 (0.41) | PLAUPLATKLKB1PRSS1PRSS2 | |
| SCHEMBL11142513 | 0.77 | POLB (0.54) | MYC | |
| SCHEMBL3355657 | 0.75 | ENPP1 (0.42) | ENPP1MYCHEXAHEXBPTGS1 | |
| SCHEMBL28628791 | 0.75 | PLAU (0.49) | PLAUPLATKLKB1PRSS1PRSS2 | |
| SCHEMBL26612817 | 0.74 | PLAU (0.49) | PLAUPLATKLKB1PRSS1PRSS2 | |
| Methane SCHEMBL11860700 | 0.74 | ENPP1 (0.41) | ENPP1MYCHEXAHEXBPTGS1 | |
| SCHEMBL7870792 | 0.73 | MYC (0.50) | PLAUPLATKLKB1PRSS1PRSS2 | |
| SCHEMBL29706607 | 0.72 | MAOA (0.43) | ENPP1PARP1PTGS1PTGS2COMT | |
| SCHEMBL4843094 | 0.72 | ADORA2A (0.50) | ENPP1PARP1HEXAHEXBPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834058-A | Organometallic complexes of aluminium, gallium and indium | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1998-11-10 | — | — | US | disclosed |
| EP-0712409-B1 | ORGANOMETALLIC COMPLEXES OF ALUMINIUM, GALLIUM AND INDIUM | ASS OCTEL (GB) | 1998-10-28 | — | — | EP | disclosed |
| EP-0712409-A1 | ORGANOMETALLIC COMPLEXES OF ALUMINIUM, GALLIUM AND INDIUM | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004063-A1 | ORGANOMETALLIC COMPLEXES OF ALUMINIUM, GALLIUM AND INDIUM | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1995-02-09 | — | — | WO | disclosed |