Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 4/20 | 0.39 |
| ▸ | PLAT | P00750 | 4/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832583 | 0.84 | BCAT2 (0.50) | PLAUPLATKLKB1PRSS1PRSS2 | |
| SCHEMBL28216060 | 0.84 | SLC6A4 (0.53) | SLC6A4SLC6A3PLAUPLATKLKB1 | |
| SCHEMBL8532468 | 0.83 | PLAU (0.39) | PLAUPLATKLKB1PRSS1PRSS2 | |
| SCHEMBL30370009 | 0.78 | BCAT2 (0.57) | SLC6A4SLC6A3PTGS2PTGS1GRM2 | |
| SCHEMBL3034724 | 0.72 | HDAC6 (0.48) | SLC6A4SLC6A3PTGS1ABL1BCAT2 | |
| SCHEMBL28248560 | 0.72 | MAOA (0.43) | SLC6A4SLC6A3PTGS2PTGS1ENPP1 | |
| SCHEMBL1005911 | 0.71 | SLC6A4 (0.44) | SLC6A4SLC6A3PTGS2PTGS1ENPP1 | |
| SCHEMBL27940786 | 0.71 | IKBKB (0.47) | SLC6A4SLC6A3GRM2BCAT2CYP1A2 | |
| SCHEMBL17558545 | 0.70 | FABP4 (0.44) | PLAUPLATKLKB1PRSS1PRSS2 | |
| SCHEMBL2543678 | 0.70 | ENPP1 (0.42) | SLC6A4SLC6A3PTGS2PTGS1ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303714-B1 | NOVEL METALLOCENE POLYMERIZATION CATALYST COMPLEXES CONTAINING ATOMS OF GROUP 15 OF THE PERIODIC TABLE, E.G., (PENTAMETHYLCYCLOPENTADIENYL)(N,N'-BIS(PHENYL)BENZAMIDINATO)ZI RCONIUM DICHLORIDE | JAPAN POLYOLEFINS CO., LTD. (JP) | 2001-10-16 | — | — | US | disclosed |
| EP-0926166-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PREPARING POLYOLEFIN | Japan Polyolefins Co., Ltd. (JP) | 1999-06-30 | — | — | EP | disclosed |