Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 5/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533404 | 0.89 | HTR2B (0.39) | SLC9A1HTR7HTR2B | |
| SCHEMBL27370429 | 0.86 | PTGS2 (0.35) | — | |
| SCHEMBL8534938 | 0.84 | SLC9A1 (0.44) | SLC9A1 | |
| SCHEMBL8529625 | 0.83 | PTGS2 (0.38) | — | |
| SCHEMBL8529748 | 0.80 | SLC9A1 (0.43) | SLC9A1 | |
| SCHEMBL8533625 | 0.79 | SLC9A1 (0.41) | SLC9A1 | |
| SCHEMBL8529278 | 0.79 | SLC9A1 (0.42) | SLC9A1 | |
| SCHEMBL8533060 | 0.75 | SLC9A1 (0.40) | SLC9A1HTR7HTR2B | |
| SCHEMBL8530215 | 0.73 | MEN1 (0.39) | — | |
| SCHEMBL8581878 | 0.73 | SLC9A1 (0.36) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699660-B1 | Arylbenzoylguanidines | MERCK PATENT GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5807896-A | Arylbenzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING (DE) | 1998-09-15 | — | — | US | disclosed |
| EP-0699660-A2 | Arylbenzoylguanidines | MERCK PATENT GmbH (DE) | 1996-03-06 | — | — | EP | disclosed |