Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 2/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529625 | 0.86 | PTGS2 (0.38) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL8534063 | 0.81 | CA1 (0.42) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL409670 | 0.76 | ALDH1A1 (0.41) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL29226029 | 0.75 | HNF4A (0.56) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL30153392 | 0.75 | HNF4A (0.56) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL8528932 | 0.74 | XDH (0.40) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL8533248 | 0.74 | FOLH1 (0.39) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL6239020 | 0.74 | BCAT2 (0.49) | MAPTALDH1A1CA1CA2CA9 | |
| SCHEMBL27370429 | 0.73 | PTGS2 (0.35) | MEN1KMT2AMAPTLMNACYP2C9 | |
| SCHEMBL8533261 | 0.73 | SLC9A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1055919-C | Arylbenzoylguanidin | MERCK PATENT GMBH (DE) | 2000-08-30 | — | — | CN | disclosed |
| EP-0699660-B1 | Arylbenzoylguanidines | MERCK PATENT GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5807896-A | Arylbenzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING (DE) | 1998-09-15 | — | — | US | disclosed |
| EP-0699660-A2 | Arylbenzoylguanidines | MERCK PATENT GmbH (DE) | 1996-03-06 | — | — | EP | disclosed |
| CN-1117962-A | Arylbenzoylguanidin | MERCK PATENT GMBH (DE) | 1996-03-06 | — | — | CN | disclosed |