SCHEMBL8534938

SCHEMBL8534938

CS(=O)(=O)c1c(-c2ccccc2)ccc(C(=O)N=C(N)N)c1F

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 5/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8533060 0.88 SLC9A1 (0.40) SLC9A1
SCHEMBL27526742 0.85 PTGS2 (0.37)
SCHEMBL8533261 0.84 SLC9A1 (0.42) SLC9A1
SCHEMBL8529748 0.82 SLC9A1 (0.43) SLC9A1
SCHEMBL8529538 0.82 PTGS2 (0.41)
SCHEMBL8529278 0.81 SLC9A1 (0.42) SLC9A1
SCHEMBL8530250 0.80 SLC9A1 (0.52) SLC9A1
SCHEMBL8532592 0.77 SLC9A1 (0.43) SLC9A1
SCHEMBL8533094 0.76 SLC9A1 (0.53) SLC9A1
SCHEMBL8533081 0.75 SLC9A1 (0.40) SLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699660-B1 Arylbenzoylguanidines MERCK PATENT GMBH (DE) 1998-10-28 EP disclosed
US-5807896-A Arylbenzoylguanidines MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING (DE) 1998-09-15 US disclosed
EP-0699660-A2 Arylbenzoylguanidines MERCK PATENT GmbH (DE) 1996-03-06 EP disclosed