Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 5/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16267526 | 0.85 | LMNA (0.50) | ALDH1A1TSHRMEN1LMNATHRB | |
| SCHEMBL5530294 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TSHRMEN1LMNATHRB | |
| SCHEMBL20305958 | 0.80 | GABRA1 (0.36) | ALDH1A1TSHRTDP1CA1CA2 | |
| SCHEMBL7178419 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TSHRMEN1LMNATHRB | |
| SCHEMBL357603 | 0.78 | GABRA1 (0.48) | ALDH1A1TSHRMEN1KMT2ACA1 | |
| SCHEMBL5525654 | 0.78 | ERN1 (0.57) | ALDH1A1TSHRMEN1LMNATHRB | |
| SCHEMBL8955156 | 0.78 | MEN1 (0.42) | ALDH1A1TSHRMEN1LMNATHRB | |
| SCHEMBL15609192 | 0.77 | PTGER3 (0.51) | CA1CA2HTTSMN1; SMN2 | |
| SCHEMBL15609193 | 0.77 | PTGER3 (0.51) | CA1CA2HTTSMN1; SMN2 | |
| Alcohol SCHEMBL27697026 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TSHRMEN1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584818-B1 | Aqueous coating compositions comprising a dispersion of a polyurethane resin, process for their preparation and their use | HERBERTS & CO GMBH (DE) | 1998-12-02 | — | — | EP | disclosed |
| EP-0584818-A1 | Aqueous polyuretane dispersions, process for their preparation and their use in aqueous coating compositions | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1994-03-02 | — | — | EP | disclosed |