SCHEMBL8955156

SCHEMBL8955156

O=Cc1cccc(CO)c1CO

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
LMNA P02545 1/20 0.42
THRB P10828 1/20 0.42
BLM P54132 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ERN1 O75460 4/20 0.42
TRIM24 O15164 1/20 0.40
TRIM33 Q9UPN9 1/20 0.40
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TLR2 O60603 1/20 0.36
TLR1 Q15399 1/20 0.36
TLR6 Q9Y2C9 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
TSHR P16473 1/20 0.35
APOBEC3G Q9HC16 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16267526 0.87 LMNA (0.50) MEN1LMNATHRBBLMKMT2A
SCHEMBL29942439 0.80 LMNA (0.55) MEN1LMNATHRBBLMKMT2A
SCHEMBL2544808 0.80 LMNA (0.55) MEN1LMNATHRBBLMKMT2A
SCHEMBL2647250 0.79 MEN1 (0.42) MEN1LMNATHRBBLMKMT2A
SCHEMBL5525654 0.79 ERN1 (0.57) MEN1LMNATHRBBLMKMT2A
SCHEMBL5519906 0.79 ERN1 (0.57) MEN1LMNATHRBBLMKMT2A
SCHEMBL216868 0.79 ALDH1A1 (0.35) MEN1LMNAKMT2AALDH1A1APOBEC3G
SCHEMBL2651603 0.79 APOBEC3G (0.34) APOBEC3GHDAC3HDAC1HDAC2HDAC6
SCHEMBL30225047 0.79 ERN1 (0.57) MEN1LMNATHRBBLMKMT2A
SCHEMBL17693447 0.79 ERN1 (0.38) MEN1LMNATHRBBLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0475605-B1 Phenolic resin and method for preparing same MITSUI TOATSU CHEMICALS (JP) 1996-01-03 EP claimed
CN-116970963-A Method for synthesizing p-hydroxymethyl benzaldehyde 南京晓庄学院 2023-10-31 CN disclosed