Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 13/20 | 0.45 |
| ▸ | MMP2 | P08253 | 11/20 | 0.45 |
| ▸ | MMP1 | P03956 | 14/20 | 0.43 |
| ▸ | MMP9 | P14780 | 10/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 4/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | MMP7 | P09237 | 2/20 | 0.40 |
| ▸ | MMP14 | P50281 | 2/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.40 |
| ▸ | MMP20 | O60882 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | MMP10 | P09238 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP15 | P51511 | 1/20 | 0.40 |
| ▸ | MMP16 | P51512 | 1/20 | 0.40 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.40 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777512 | 0.73 | MMP3 (0.59) | MMP3MMP2MMP1MMP9MMP8 | |
| SCHEMBL8537928 | 0.73 | GPR88 (0.47) | POLBCTDSP1 | |
| SCHEMBL8777490 | 0.73 | POLB (0.38) | MMP3MMP2MMP1MMP9POLB | |
| SCHEMBL6435917 | 0.73 | POLB (0.38) | MMP3MMP2MMP1MMP9POLB | |
| SCHEMBL17663573 | 0.70 | MMP3 (0.41) | MMP3MMP2MMP1MMP9POLB | |
| SCHEMBL8534029 | 0.69 | MMP3 (0.38) | MMP3MMP2MMP1MMP9POLB | |
| SCHEMBL5860242 | 0.66 | SLC1A3 (0.48) | POLBCTDSP1 | |
| SCHEMBL9635454 | 0.66 | FOLH1 (0.32) | MMP3MMP2 | |
| SCHEMBL8410837 | 0.65 | CA1 (0.46) | MMP3MMP2 | |
| SCHEMBL30076538 | 0.64 | ALDH1A1 (0.35) | MMP3MMP2MMP1MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849951-A | Synthesis of carboxylic and hydroxamic acid derivatives | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-12-15 | — | — | US | disclosed |