Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 7/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533445 | 0.73 | MMP3 (0.45) | POLBCTDSP1 | |
| SCHEMBL8534969 | 0.73 | SMN1; SMN2 (0.38) | GPR88POLBKEAP1NFE2L2TXNRD1 | |
| SCHEMBL8534971 | 0.70 | TXNRD1 (0.39) | GPR88POLBKEAP1NFE2L2TXNRD1 | |
| SCHEMBL5156721 | 0.67 | POLB (0.50) | POLBCTDSP1CNR1CNR2ACHE | |
| SCHEMBL13611896 | 0.65 | GPR88 (0.49) | GPR88POLBANPEPSMN1; SMN2 | |
| SCHEMBL11266612 | 0.64 | USP2 (0.44) | GPR88POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4598036 | 0.62 | CTSK (0.67) | GPR88 | |
| SCHEMBL4598033 | 0.62 | CTSK (0.67) | GPR88 | |
| SCHEMBL8513252 | 0.61 | CTSS (0.52) | KEAP1NFE2L2 | |
| SCHEMBL12195416 | 0.61 | CTSS (0.52) | KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849951-A | Synthesis of carboxylic and hydroxamic acid derivatives | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-12-15 | — | — | US | disclosed |
| EP-0812312-A1 | SYNTHESIS OF CARBOXYLIC AND HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-12-17 | — | — | EP | disclosed |
| WO-1996026918-A1 | SYNTHESIS OF CARBOXYLIC AND HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-09-06 | — | — | WO | disclosed |