Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MYOC | Q99972 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534580 | 0.90 | GAA (0.43) | FPR1FPR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL4605520 | 0.76 | TSHR (0.50) | KMT2AMEN1ALDH1A1HTTCYP19A1 | |
| SCHEMBL4836695 | 0.73 | POLB (0.51) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL8773924 | 0.73 | CRHBP (0.39) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL8773928 | 0.73 | CRHBP (0.39) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL7547943 | 0.73 | MEN1 (0.41) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL6261538 | 0.72 | MAPT (0.62) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL15559316 | 0.70 | MGLL (0.46) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL3573967 | 0.70 | MAPT (0.66) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL8773979 | 0.69 | BRD4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |