Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 3/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 5/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773924 | 1.00 | CRHBP (0.39) | CRHBPCRHR2ARRIPK1ALDH1A1 | |
| SCHEMBL8773926 | 0.80 | SNCA (0.33) | ARALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4605520 | 0.78 | TSHR (0.50) | RIPK1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4836695 | 0.75 | POLB (0.51) | RIPK1ALDH1A1MEN1KMT2APKM | |
| SCHEMBL8534580 | 0.73 | GAA (0.43) | ALDH1A1MEN1KMT2AATMHTT | |
| SCHEMBL8533492 | 0.73 | FPR1 (0.45) | CRHBPCRHR2ALDH1A1MEN1KMT2A | |
| SCHEMBL21247872 | 0.72 | ALDH1A1 (0.67) | CRHBPCRHR2ALDH1A1MEN1KMT2A | |
| SCHEMBL29182467 | 0.71 | ALDH1A1 (0.57) | CRHBPCRHR2ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9542971 | 0.69 | KCNH2 (0.42) | ALDH1A1MEN1KMT2AL3MBTL1ATM | |
| SCHEMBL1873509 | 0.69 | MAPK1 (0.52) | CRHBPCRHR2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |