Diphenylether

Diphenylether

SCHEMBL8533552

CCC(=O)O.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.57
TSHR P16473 1/20 0.57
FFAR1 O14842 1/20 0.57
HPGD P15428 2/20 0.53
NPC1 O15118 1/20 0.53
CRHBP P24387 1/20 0.53
RAB9A P51151 1/20 0.53
CRHR2 Q13324 1/20 0.53
ALOX15 P16050 1/20 0.52
PARP10 Q53GL7 1/20 0.52
SRD5A2 P31213 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
AKR1C3 P42330 1/20 0.50
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL7197965 0.96 FFAR1 (0.53) LTA4HTSHRFFAR1HPGDNPC1
Diphenylether SCHEMBL6560478 0.94 FFAR1 (0.52) LTA4HTSHRFFAR1HPGDNPC1
Propionic Acid SCHEMBL8675361 0.90 LTA4H (0.69) LTA4HFFAR1HPGDNPC1CRHBP
Diphenylether SCHEMBL27521612 0.88 LTA4H (0.55) LTA4HTSHRFFAR1HPGDNPC1
Diphenylether SCHEMBL7033901 0.88 LTA4H (0.60) LTA4HTSHRFFAR1HPGDNPC1
Diphenylether SCHEMBL6560849 0.87 NPY5R (0.49) LTA4HFFAR1HPGDNPC1CRHBP
Anisole SCHEMBL7429921 0.84 CA4 (0.64) LTA4HNPC1RAB9AALOX15SMN1; SMN2
Diphenylether SCHEMBL3353061 0.83 LTA4H (0.60) LTA4HTSHRFFAR1ALOX15PARP10
Diphenylether SCHEMBL27775292 0.83 LTA4H (0.60) LTA4HTSHRFFAR1HPGDNPC1
Diphenylether SCHEMBL5918274 0.83 FFAR1 (0.70) LTA4HTSHRFFAR1ALOX15PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109778568-A A kind of fabric dyeing toner for nylon 丹阳市易通安全技术服务有限公司 2019-05-21 CN claimed
CN-110914241-B Propionic acid derivatives and methods of use thereof 阿维亚拉药品有限公司 2023-11-14 CN disclosed
CN-110914241-A Propionic acid derivatives and methods of use thereof 阿维亚拉药品有限公司 2020-03-24 CN disclosed
CN-109778568-A A kind of fabric dyeing toner for nylon 丹阳市易通安全技术服务有限公司 2019-05-21 CN disclosed
CN-109778568-A A kind of fabric dyeing toner for nylon 丹阳市易通安全技术服务有限公司 2019-05-21 CN disclosed
US-5718919-A Nanoparticles containing the R(-)enantiomer of ibuprofen NANOSYSTEMS L.L.C. (US) 1998-02-17 US disclosed