Diphenylether

Diphenylether

SCHEMBL3353061

O=C(O)CO.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.60
TSHR P16473 1/20 0.60
FFAR1 O14842 2/20 0.59
ALOX15 P16050 1/20 0.54
PARP10 Q53GL7 1/20 0.54
SRD5A2 P31213 4/20 0.53
NR1H2 P55055 1/20 0.52
BAX Q07812 1/20 0.52
AKR1C3 P42330 1/20 0.52
ERCC5 P28715 1/20 0.50
FEN1 P39748 1/20 0.50
FFAR4 Q5NUL3 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
RNF4 P78317 1/20 0.48
GSTP1 P09211 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL5918274 0.85 FFAR1 (0.70) LTA4HTSHRFFAR1ALOX15PARP10
Diphenylether SCHEMBL27775292 0.85 LTA4H (0.60) LTA4HTSHRFFAR1ALOX15PARP10
Diphenylether SCHEMBL1965337 0.84 LTA4H (0.75) LTA4HTSHRFFAR1PARP10SRD5A2
Diphenylether SCHEMBL360280 0.84 LTA4H (0.75) LTA4HTSHRFFAR1PARP10SRD5A2
Diphenylether SCHEMBL5606885 0.84 LTA4H (0.75) LTA4HTSHRFFAR1PARP10SRD5A2
Diphenylether SCHEMBL8533552 0.83 LTA4H (0.57) LTA4HTSHRFFAR1ALOX15PARP10
Diphenylether SCHEMBL19951674 0.83 LTA4H (0.57) LTA4HTSHRFFAR1ALOX15PARP10
Diphenylether SCHEMBL27352413 0.82 FFAR1 (0.52) LTA4HTSHRFFAR1ALOX15PARP10
Diphenylether SCHEMBL6560478 0.82 FFAR1 (0.52) LTA4HTSHRFFAR1ALOX15PARP10
Diphenylether SCHEMBL8837235 0.81 LTA4H (0.71) LTA4HTSHRFFAR1PARP10SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004091307-A2 FEED ADDITIVES AGAINST DISEASSE INFECTION IN TERRESTRIAL AND AQUATIC ANIMALS ADVANCED BIONUTRITON CORPORATION (US) 2004-10-28 WO claimed
CN-105031697-A Deodorant for bathroom and preparation method of deodorant SUZHOU KEMIAO NEW MAT CO LTD 2015-11-11 CN disclosed
US-20150073045-A1 POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO CORNELL UNIVERSITY (US) 2015-03-12 US disclosed
US-20140128458-A1 POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO CORNELL UNIVERSITY (US) 2014-05-08 US disclosed
US-8563603-B2 Polycyclic compounds and methods related thereto CORNELL UNIVERSITY (US) 2013-10-22 US disclosed
US-20120225053-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF CONDITIONS ASSOCIATED WITH INFLAMATION DUSHENKOV SLAVIK (US) 2012-09-06 US disclosed
WO-2010048452-A2 POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO CHAVEZ KATHRYN JILL (US) 2010-04-29 WO disclosed
US-7638114-B1 Method for disinfecting the air SCHUER JOERG PETER 2009-12-29 US disclosed
US-7351739-B2 Bioactive compounds and methods of uses thereof WELLGEN, INC. (US) 2008-04-01 US disclosed
US-20080045587-A1 PLANT PROTECTION SCHUR JORG P 2008-02-21 US disclosed
US-7108879-B2 Process for improving the durability of, and/or stabilizing, microbially perishable products SCHUR JORG PETER 2006-09-19 US disclosed
WO-2006073457-A2 BIOACTIVE COMPOUNDS AND METHODS OF USES THEREOF RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2006-07-13 WO disclosed
US-20060052438-A1 Bioactive compounds and methods of uses thereof REGENTS OF UNIVERSITY OF MINNESOTA, THE 2006-03-09 US disclosed
US-20050014827-A1 Synergistic medicament containing flavoring agents and having an antagonistic regenerative and/or protagonist decontamination effect SCHUR JORG P (DE) 2005-01-20 US disclosed
WO-2004091307-A2 FEED ADDITIVES AGAINST DISEASSE INFECTION IN TERRESTRIAL AND AQUATIC ANIMALS ADVANCED BIONUTRITON CORPORATION (US) 2004-10-28 WO disclosed
US-20040101459-A1 Method for neutralising odours in the air in a non-toxic manner SCHUR JORG PETER (DE) 2004-05-27 US disclosed
US-20040076614-A1 Symbiotic regenerative agent SCHUR JORG P (DE) 2004-04-22 US disclosed
US-20030198718-A1 Process for improving the durability of, and/or stabilizing, microbially perishable products SCHUR JORG PETER (DE) 2003-10-23 US disclosed
US-6514551-B1 Adjuvant comprising microbicidally active flavoring agent; cutting agent which comprises an antimicrobial composition of benzyl alcohol, flavoring polyphenol and a vegetable oil SCHUR JORG PETER (DE) 2003-02-04 US disclosed
US-20020176882-A1 Additive the improvement and/or stabilization of the keeping quality of microbially perishable products SCHUR JORG PETER (DE) 2002-11-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150073045-A1 POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO PKD1, THPO, CCNO LTA4H 1712/4885TSHR 4780/4885FFAR1 1880/4885
US-20140128458-A1 POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO PKD1, THPO, CCNO LTA4H 1712/4885TSHR 4780/4885FFAR1 1880/4885
US-20060052438-A1 Bioactive compounds and methods of uses thereof VIP, KLK3, GUSB LTA4H 528/4885TSHR 4799/4885FFAR1 4043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.