Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.55 |
| ▸ | MMP9 | P14780 | 6/20 | 0.55 |
| ▸ | MMP12 | P39900 | 6/20 | 0.55 |
| ▸ | MMP14 | P50281 | 2/20 | 0.55 |
| ▸ | MMP15 | P51511 | 1/20 | 0.55 |
| ▸ | MMP16 | P51512 | 1/20 | 0.55 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27497689 | 0.85 | MMP2 (0.50) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL11795699 | 0.83 | MMP2 (0.51) | MMP2MMP9MMP12MMP14SMN1; SMN2 | |
| SCHEMBL11405755 | 0.81 | PTPN1 (0.50) | MMP2MMP9MMP12MMP14SMN1; SMN2 | |
| SCHEMBL8535927 | 0.79 | ALDH1A1 (0.49) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL8114344 | 0.77 | MMP2 (0.73) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL5499422 | 0.76 | FFAR1 (0.59) | MMP2MMP9MMP12MMP14LMNA | |
| SCHEMBL8120164 | 0.76 | MMP2 (0.71) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL1164038 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAFFAR1CYP1A2RAB9A | |
| SCHEMBL27992180 | 0.74 | MMP2 (0.59) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL11139907 | 0.74 | NPC1 (0.54) | MMP2MMP9MMP12SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216522-A | Therapeutic agent for diabetes | JAPAN TOBACCO INC (JP) | 1999-05-12 | — | — | CN | disclosed |
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |