Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | MMP15 | P51511 | 1/20 | 0.43 |
| ▸ | MMP16 | P51512 | 1/20 | 0.43 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27497689 | 0.96 | MMP2 (0.50) | ALDH1A1MEN1KMT2AL3MBTL1HTT | |
| SCHEMBL8533584 | 0.79 | MMP2 (0.55) | ALDH1A1L3MBTL1HTTSMN1; SMN2MAPT | |
| SCHEMBL6341119 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ANPC1MAPT | |
| SCHEMBL11244038 | 0.78 | KMT2A (0.54) | ALDH1A1MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL4270804 | 0.76 | MAPT (0.61) | ALDH1A1MEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL11732434 | 0.76 | KMT2A (0.53) | ALDH1A1MEN1KMT2AL3MBTL1HTT | |
| SCHEMBL8532867 | 0.75 | KMT2A (0.60) | ALDH1A1MEN1KMT2AL3MBTL1HTT | |
| SCHEMBL24106782 | 0.75 | MEN1 (0.70) | ALDH1A1MEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL570961 | 0.75 | MEN1 (0.70) | ALDH1A1MEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL7752972 | 0.75 | SMN1; SMN2 (0.65) | ALDH1A1MEN1KMT2AL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |